Signal p Peptide signaling, a fundamental process involving small protein fragments, orchestrates a vast array of biological functions, particularly within plant development and cellular communication. These signaling peptides act as vital messengers, relaying information to coordinate complex processes such as cell proliferation, differentiation, and responses to environmental cuesSignal Peptides: From Molecular Mechanisms to .... Understanding peptide signaling is key to comprehending how plants grow, develop, and interact with their surroundings, even at the remarkably low concentrations at which they operate作者：C Furumizu·2023·被引用次数：37—Several small post-translationally modifiedpeptides(PTMPs) have been identified as components of cell-to-cellsignalingmodules in flowering plants..
A significant aspect of peptide signaling involves signal peptides.Signal Peptides: Essential Elements of Protein Targeting ... These are short amino acid sequences, typically found at the N-terminus of nascent proteinsPeptide Signaling in Flowering Plants: Insights into .... Their primary function is to direct proteins to their correct cellular destinations, particularly those destined for secretion or insertion into membranes. Signal peptides act like molecular zip codes, ensuring that proteins are transported through the secretory pathway and reach their designated locations within or outside the cell. This precise targeting is crucial for the proper functioning of cellular machinery and the overall health of the organism.作者：CJ Perkins·2025·被引用次数：2—Flowering plants use small, secreted peptidesto initiate complex signaling cascades that coordinate essential developmental processes and ...
In plants, peptide signaling plays an indispensable role in regulating growth and development. Various families of signaling peptides have been identified, each with specific functions. For instance, Root Meristem Growth Factors (RGFs) are a class of orphan peptides that are critical for controlling root growth by influencing the expression and gradient of transcription factors.Peptide Signaling in Plants | Frontiers Research Topic Similarly, secreted signaling peptides are vital for intercellular communication, guiding vascular development through short-range signaling. This intricate peptide-mediated communication network ensures that plants can coordinate complex developmental processes, from the formation of roots to the development of reproductive structures.作者：S Zhang·2025·被引用次数：11—Signal peptides (SPs) areshort amino acid sequences located at the N-terminus of nascent proteinsand are widely present across various life forms.
The discovery of Tomato systemin as the first identified plant signaling peptide highlighted the importance of these molecules in mediating systemic responses, such as wound responsesSignaling Peptide - an overview. More recently, research has revealed the involvement of other peptides like Phytosulfokine (PSK), a peptide hormone known for its growth-promoting properties, in regulating processes like drought-induced flower drop in tomato plants. These examples underscore the diverse and critical roles that peptide signaling plays in plant physiology作者：MJ Kim·2021·被引用次数：53—Plant signaling peptides are involved in cell–cell communication networksand coordinate a wide range of plant growth and developmental processes..
Peptide signaling in plants often involves small, secreted peptides that bind to specific receptor complexes, typically leucine-rich repeat receptor kinases (LRR-RKs) located on the plasma membraneA comprehensive review of signal peptides: Structure, roles .... Upon binding, these receptors initiate intracellular signaling cascades that ultimately lead to changes in gene expression and cellular responses. This mechanism allows plants to perceive and respond to a wide range of stimuli, including developmental signals and environmental challenges.
Beyond growth and development, peptide signaling is also implicated in plant defense mechanisms. Danger-associated peptide signaling, for example, has been shown to be involved in inducing plant defense responses, highlighting the broad impact of these molecules. The ability of plants to utilize peptides for complex signaling pathways, even at femtomolar concentrations, demonstrates a sophisticated communication system essential for their survival and adaptation.作者：S Zhang·2025·被引用次数：11—Signal peptides (SPs) areshort amino acid sequences located at the N-terminus of nascent proteinsand are widely present across various life forms.
The field of peptide signaling continues to expand, with ongoing research uncovering new peptide families and their roles in various biological processes.作者：I Dogsa·2021·被引用次数：32—The SMpeptideComX encodes the information about cell density, specific cell growth rate, and even oxygen concentration, which ensure power-law increase in SM ... For example, Rapid Alkalinization Factor (RALF) peptides are known to control pollen tube reception and rupture, crucial steps in plant reproduction. As our understanding deepens, it is becoming clear that peptide signaling is a fundamental and versatile mechanism that underpins much of plant life.作者：B Yusta·2009·被引用次数：134—Background & Aims: Glucagon-likepeptide-2 (GLP-2) is a 33-amino acidpeptidehormone secreted by enteroendocrine cells in response to nutrient ingestion. Further research promises to unlock new insights into plant biology, potentially leading to applications in agriculture and crop improvement by harnessing these powerful signaling molecules.
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