acvr2b-peptide The ACQUITY UPLC M-Class Peptide BEH C18 column stands as a critical component for advanced liquid chromatographic separations, particularly within the realm of peptide analysis and biomarker discovery. Designed by Waters Corporation, these columns are engineered for optimal performance at the nano- to micro-scale, offering researchers the sensitivity and resolution necessary for complex biological samples. The "M-Class" designation signifies a system optimized for these smaller flow rates and higher pressures, crucial for achieving high peak capacity in demanding analytical workflowsWaters Corp ACQUITY UPLC M-Class Peptide CSH C18 ....
At its core, the ACQUITY UPLC M-Class Peptide BEH C18 column is a specialized tool for separating and analyzing peptides.Shop ACQUITY UPLC M-Class Peptide BEH C18 Column The "BEH" in its name refers to the Ethylene Bridged Hybrid (BEH) particle technology, a key innovation that allows these columns to withstand high pressures, up to 15,000 psi (1034 Bar), while maintaining excellent chromatographic performance.品名：ACQUITYUPLCM-Class PeptideBEH C18Column, 130Å, 1.7 µm, 75 µm X 250 mm, 1/pk ; 货号：186007484 ; 品牌：Waters ; 规格：1/pk ; 产品描述. This robust particle technology is fundamental to achieving reproducible and reliable separations, especially when dealing with intricate peptide mixtures.
The C18 (octadecylsilane) stationary phase is a widely used reversed-phase material. Its non-polar nature interacts with hydrophobic regions of peptides, allowing for separation based on hydrophobicity.The ACQUITY UPLC M-Class Column ought to be a part of your laboratory because it wasdesigned for liquid chromatographic separation on a nano- to micro-scale. This makes it highly effective for a broad range of peptide applications, from small peptides to larger protein fragments. The combination of BEH particle technology and the C18 phase in an M-Class column format is specifically tailored for nano- to micro-scale liquid chromatographic separations, maximizing sensitivity and efficiency.
ACQUITY UPLC M-Class Peptide BEH C18 columns are available in various configurations to suit different analytical needs. Common specifications include:
* Particle Size: Typically 1.Waters, 186007486, ACQUITY UPLC M-Class Peptide ...7 µm, which contributes to higher efficiency and resolution compared to larger particles.Waters 186007485 Acquity Uplc M-class Peptide Beh C18 Column; Product SKU: 137979 ;. Free Delivery ;. Top Brand ;. Secure Payment ; Pn · 186007485
* Column Dimensions: Various lengths and internal diameters are offered, such as 150 µm x 100 mm, 75 µm x 100 mm, 75 µm x 200 mm, and 75 µm x 250 mm. The smaller internal diameters are characteristic of nano- and micro-scale chromatography, enabling reduced solvent consumption and increased sensitivity.
* Pore Size: Often specified in Angstroms (Å), such as 130 Å or 300 Å.UPLC Column ACQUITY M-Class Peptide BEH C18 100 ... The pore size influences the access of analytes to the stationary phase surface and is critical for the separation of molecules of different sizes.Waters 186007481 ACQUITY UPLC M-Class Peptide BEH ...
* Pressure Tolerance: Designed to handle high operating pressures (up to 15,000 psi), essential for Ultra-High-Performance Liquid Chromatography (UHPLC) systems like the ACQUITY UPLC M-Class System.Bioz Stars score, Techniques, Protocol Conditions and more forAcquity Uplc M Class Peptide Beh C18 Nanoacquity Column10k Psi, supplied by Waters ...
These specifications collectively contribute to the column's ability to deliver high peak capacity, excellent sensitivity, and reproducible results essential for applications like biomarker discovery, protein identification, and characterization.
The ACQUITY UPLC M-Class Peptide BEH C18 column is a preferred choice for several demanding analytical workflows:
* Biomarker Discovery: Identifying and quantifying low-abundance peptides in complex biological matrices such as plasma, serum, or cell lysates. The high sensitivity and resolution of these columns are crucial for detecting subtle changes associated with disease states.The 75mm to 180mm inner diametercolumnsfeature a novel frit technology that can withstand an operating pressure of 15kpsi and tolerate pressure fluctuations ...
* Protein Identification and Characterization: Used in conjunction with mass spectrometry (MS), these columns enable detailed analysis of protein digests, aiding in protein identification, post-translational modification analysis, and sequence verificationWaters 186007485 Acquity Uplc M-class Peptide Beh C18 Column; Product SKU: 137979 ;. Free Delivery ;. Top Brand ;. Secure Payment ; Pn · 186007485.
* Peptide Mapping: Generating characteristic fingerprints of proteins by analyzing the peptides produced after enzymatic digestion. This technique is vital for quality control of biopharmaceuticals and for characterizing subtle differences between protein variants.
* Metabolomics and Proteomics Research: Contributing to the broader fields of metabolomics and proteomics by providing precise separation of peptide and small molecule analytesACQUITY UPLC M-Class Columnsare engineered for peptide and protein separations, nano- and microflow liquid chromatography, and efficient UPLC/MS coupling..
The ability of these columns to perform efficient separations at nano- to micro-flow rates minimizes sample dilution and enhances ionization efficiency when coupled with mass spectrometers, leading to improved detection limits.This Item:Waters Corp ACQUITY UPLC M-Class Peptide BEH C18 Column, 300Å, 1.7 µm, 150 µm X 100 mm, 1/pk;. ,207.89 / Each.
While the BEH C18 is a workhorse, Waters also offers other ACQUITY UPLC M-Class columns, such as the Peptide CSH C18. The CSH (Charged Surface Hybrid) technology in the CSH C18 columns offers unique selectivity, particularly for peptides with ionizable groups, and can provide orthogonal selectivity compared to BEH C18.ACQUITY UPLC M-Class Peptide BEH C18 Column, 300à , 1.7 µm, 75 µm X 250 mm, 1/pk. Catalog No. 50-239-1170. Sign In or Register to check your price ... This makes the choice between BEH C18 and CSH C18 dependent on the specific analytical challenge and the nature of the peptides being analyzed. For general peptide separations where hydrophobicity is the primary separation mechanism, the BEH C18 is often the go-to choice due to its broad applicability and robust performanceAcquity Uplc M Class Peptide Beh C18 Nanoacquity ....
In conclusion, the ACQUITY UPLC M-Class Peptide BEH C18 column is an indispensable tool for researchers requiring high-performance liquid chromatography for peptide analysisU(H)PLC Column ACQUITY M-Class Peptide BEH C18, 300 Å .... Its advanced particle technology, optimized dimensions, and robust design enable sensitive, reproducible, and efficient separations, driving progress in fields ranging from drug discovery to fundamental biological research.
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